Care managers have an ethical duty to maintain healthy relationships with clients, based upon an understanding of transference, value conflicts and confidentiality. These and other key principles, including informed consent and client rights, are detailed in this module. The care manager’s role in relation to protected and vulnerable populations is also explored, with an emphasis on working with seniors and persons with disabilities and dually eligible Medicaid and Medicare populations. Care managers are taught and given the opportunity to apply best practice interventions that positively modify client behaviors.