Research demonstrates that when patients are activated – that is fully engaged in managing their own health care – they are more likely to achieve their care goals. Activated patients have the knowledge, skills, and willingness to become full participants in their care plan development and implementation. This essential module explores patient activations, focusing on client roles in the process, opportunities to improve client knowledge, skills, and confidence, cultivating client self-advocacy, and promoting long-term empowerment and resilience.